Apply for funding

We are focusing on the assessment of the rapalog drug class to develop treatment options for specific symptoms of PHTS which may bring meaningful benefit to patients.

We are also interested in testing alternative therapy options to rapalogs. To identify such alternatives, we are interested in the development of in vitro and in vivo models of PHTS. This will support research to identify and/or validate cellular drug targets with the aim of generating evidence to justify clinical testing.

We want to improve the understanding of the risk of cancer in PHTS, and how those with PHTS who develop cancer respond to currently available cancer treatments. We also want to investigate ways to improve the screening and detection of malignancies in PHTS.

We will support research to address key unknowns of PHTS relating to its pathobiology, complete clinical spectrum, epidemiology, and the unmet need.

Applications should be made in line with requirements detailed for the specific call. There are currently no open targeted calls accepting applications. Targeted calls will be announced on our website, social media and other appropriate platforms. To keep up to date on our targeted call opportunities consider signing up to our newsletter.

PTEN Research will acknowledge the submission of application within a week of receipt. All applications will be checked for completion. If an application does not meet the mandatory eligibility criteria, as specified by the targeted call, it will not be processed and will be returned to the applicant.

All applications will undergo scientific, budgetary and programmatic assessment by our scientific research team followed by external peer review by a minimum of two independent experts. Applicants will be provided with feedback on their application and will have an opportunity to respond to any specific questions raised.

All applications are assessed by our Scientific Advisory Board before the final funding decision is made by our Trustee Board.

For any more information about applications please contact research@ptenresearch.org.

Applications for seed funding will be accepted on an ongoing basis. The application form can be downloaded here. Please send the completed application form to research@ptenresearch.org.

To be eligible to apply for a Seed Funding award, applications should not exceed 15,000 GBP (or equivalent in local currency at the date of submission) and, in general, not exceed a duration of 1 year. In addition to the costs excluded here, Seed Funding awards are not intended to cover staffing costs.

PTEN Research will acknowledge the submission of applications within a week of receipt. All applications will be checked for completion and, where necessary, applicants may be contacted for further clarification on the specifics of the application prior to review. If an application does not meet the mandatory eligibility criteria for seed funding, it will not be processed and will be returned to the applicant.

Applications will be reviewed twice a year by the internal scientific team. The final funding agreement will be agreed by our Trustee Board.

Funding decisions will be made in April and October of each year. To be considered for the next application review date, applications must be submitted by the 15th of March or the 15th of September.

For any further clarification or questions relating to our application process, please contact research@ptenresearch.org.

Successful seed funding awardees are welcome, upon the completion of the award, to seek follow-on funding via an innovation award.

Outside of the processes discussed above, the Foundation remains open to new opportunities. To be considered for funding opportunities, applicants may contact the Foundation discuss their ideas by emailing us at research@ptenresearch.org or complete the short (3-page) project proposal form.

Project proposal applications will be accepted on an ongoing basis. The project proposal form can be downloaded here. Please send the completed forms to research@ptenresearch.org.

Only projects that represent exceptional research opportunities that are aligned with the Foundation’s research strategy will be requested for a full grant application form, which will be subject to internal review, external peer review, SAB and Trustee review. Timelines associated with the review of applications will be provided upon submission of grant applications.

For any further clarification or questions relating to our application process, please contact research@ptenresearch.org.