Prof Eng is a physician-scientist and leads genomic medicine at the Cleveland Clinic. She is the Medical Director of the PTEN/Cowden Multi-Care Clinic at the Cleveland Clinic Health System, and acts as a Coordinator/Chair of the International Cowden/PTEN Consortium.
Her research programme investigates the genetics and clinical outcomes, as well as basic mechanisms, relevant to PTEN mutations and PTEN dysfunction. She is actively collaborating with multidisciplinary groups across the country to determine the mechanisms within the PTEN alterations that lead to cancer risk and/or to autism risk. Prof Eng holds a BA with honours, MD and PhD from the University of Chicago, and received internal medicine training and medical oncology fellowship training at Boston's Beth Israel Hospital and Dana-Farber Cancer Institute, respectively. She then received unique training in research and clinical care in clinical cancer genetics at the University of Cambridge and the Royal Marsden Hospital, England. As an author/co-author of over 500 peer reviewed articles, she has received numerous awards and honours including election to the National Academy of Medicine in 2010 and the 2018 American Cancer Society Medal of Honor.
Prof Eng is the current Chair of the Scientific Advisory Board.